FerAppease
Categories
Bovine
What is FerAppease mBAS?
FerAppease was developed by FERA Diagnostics & Biologicals to reduce stress and improve welfare and performance in both beef and dairy cattle.
The active ingredient of FerAppease is a synthetic analogue of the Maternal Bovine Appeasing Substance (mBAS). mBAS is naturally secreted by the sebaceous gland located on the skin of the mammary gland with the unique function of inducing an appeasing effect.
How does FerAppease work in cattle?
FerAppease is topically applied to cattle above the muzzle and in the divot behind the poll.
The active ingredient, a synthetic analogue of the Maternal Bovine Appeasing Substance (mBAS) is assimilated by the vomeronasal gland located in the nose of the animals.
The mBAS stimulation of the vomeronasal gland desensitizes regions of the amygdala and the hypothalamus, dramatically decreasing threat perception and its downstream stress consequences.
How do you apply FerAppease on cattle?
FerAppease should only be used on healthy cattle, applied topically above the muzzle and in the divot behind the poll.
When can FerAppease be used in cattle?
FerAppease can and should be used every time cattle are exposed to management and physiological stressors where suppression of threat perception is desirable including:
- weaning
- dehorning
- castration
- branding
- transportation
- commingling
- vaccination
- parturition
- interruption of lactation (dry off)
- breeding
What is the dosage of FerAppease on cattle?
> 200 lb: Apply 5 mL of FerAppease behind the poll and a second 5 mL application to the skin above the muzzle.
< 200 lb: Apply 2.5 mL of FerAppease behind the poll and a second 2.5 mL application to the skin above the muzzle.
How quickly does FerAppease start working in cattle?
Behavior modulation and stress mitigation starts to take place immediately after FerAppease is applied to cattle.
Do you need a prescription to use FerAppease in cattle?
No, FerAppease does not require a veterinarian's prescription or a Veterinary Feed Directive plan for use in beef or dairy cattle.
How much does FerAppease cost per dose for cattle?
> 200 lb - 10 mL dose: $3.00 per head
< 200 lb - 5 mL dose: $1.50 per head
Does FerAppease have any side effects in cattle?
FerAppease is considered safe for use in cattle, with no known side effects reported.
Is there a withdrawal period after using FerAppease on cattle?
No, there is no meat or milk withdrawal period after treating cattle with FerAppease.
Can FerAppease be applied to cattle when it’s raining?
FerAppease is an oil-based product, so it should be applied to dry cattle. For best results, allow at least 30 minutes for FerAppease to absorb into the skin before cattle get wet.
How long does each FerAppease application last in cattle?
One application of FerAppease is effective for 14 days. Because most stressful events in cattle last less than two weeks, a single treatment supports them throughout the entire challenge period.
Should FerAppease be reapplied to cattle after 14-days?
If cattle are being run through the chute after the 14-day period for any reason, such as revaccinating, studies have shown there are benefits to reapplying FerAppease at this time.
Does FerAppease mBAS expire?
FerAppease mBAS has a shelf life of two years. It can be stored safely until its expiration date.
How should FerAppease mBAS be stored?
FerAppease should be kept at controlled room temperature between 10–30℃ (50–86℉). Do not refrigerate or freeze.
Is FerAppease mBAS a generic version of another product?
No. FerAppease is a proprietary product developed by FERA Diagnostics & Biologicals.
Is a FerAppease applicator available?
Yes, the FerAppease Pour-On Gun is a specialized applicator designed to administer FerAppease 300 mL solutions to cattle, allowing for precise, controlled dosing directly onto the animals’ skin. The Line Fed Pour-On Applicator is also available for 1 L bottles of FerAppease.
In what sizes is FerAppease available for cattle?
FerAppease mBAS is available in two convenient sizes: a 300 mL bottle and a 1 L bottle.
Is FerAppease patented or trademarked?
Yes. FerAppease is protected under U.S. Patent No. 12,310,937, with additional patents pending. The FerAppease® trademark is registered under No. 7,084,410 as of June 20, 2023.
Can I request the full study data for FerAppease in cattle?
Yes. To request the complete bovine study data for FerAppease, please email us at inquiry@feraah.com
Swine
What is FerAppease mSAS?
FerAppease was first developed by FERA Diagnostics & Biologicals to reduce stress and enhance welfare and performance in cattle. Building on that success, it is now also used in swine, where it delivers proven stress‑reduction benefits that support pig welfare and productivity.
The active ingredient of FerAppease is a synthetic analogue of the Maternal Swine Appeasing Substance (mSAS). mSAS is naturally secreted by the sebaceous gland located on the skin of the mammary gland with the unique function of inducing an appeasing effect.
How does FerAppease work in swine?
FerAppease is topically applied to pigs skin above the muzzle to the forehead.
The active ingredient, a synthetic analogue of the Maternal Swine Appeasing Substance (mSAS) is assimilated by the vomeronasal gland located in the nose of the animals.
The mSAS stimulation of the vomeronasal gland desensitizes regions of the amygdala and the hypothalamus, dramatically decreasing threat perception and its downstream stress consequences.
How do you apply FerAppease on swine?
FerAppease should only be used on healthy pigs, applied topically to the skin above the muzzle to the forehead.
When can FerAppease be used in swine?
FerAppease can and should be used every time animals are exposed to management and physiological stressors where suppression of threat perception is desirable including:
- weaning
- castration
- vaccination
- processing
- commingling
- transportation
- farrowing
- interruption of lactation (dry off)
- breeding
- heat stress mitigation
- show training
- show days
What is the dosage of FerAppease on swine?
For piglets apply 3 mL of FerAppease from the skin above the muzzle to the forehead.
For adult pigs apply 10 mL from the skin above the muzzle to the forehead.
How quickly does FerAppease start working in swine?
Behavior modulation and stress mitigation starts to take place immediately after FerAppease is applied to pigs.
Do you need a prescription to use FerAppease in swine?
No, FerAppease does not require a veterinarian's prescription or a Veterinary Feed Directive plan for use in pigs.
How much does FerAppease cost per dose for pigs?
Adult Pigs: $0.68 cents per head
Piglets: $0.20 cents per head
Show Pigs: $1.67 per 5 mL dose or $3.33 per 10 mL dose
Does FerAppease have any side effects in pigs?
FerAppease is considered safe for use in swine, with no known side effects reported.
Is there a withdrawal period after using FerAppease on pigs?
No, there is no meat or milk withdrawal period after treating pigs with FerAppease.
Can FerAppease be applied to pigs when it’s raining?
FerAppease is an oil-based product, so it should be applied to dry pigs. For best results, allow at least 30 minutes for FerAppease to absorb into the skin before pigs get wet.
How long does each FerAppease application last in swine?
One application of FerAppease is effective for 14 days. Because most stressful events in swine last less than two weeks, a single treatment supports them throughout the entire challenge period.
Should FerAppease be reapplied to swine after 14-days?
If swine are being run through the chute after the 14-day period for any reason, such as revaccinating, studies have shown there are benefits to reapplying FerAppease at this time.
Does FerAppease mSAS expire?
FerAppease mSAS has a shelf life of two years. It can be stored safely until its expiration date.
How should FerAppease mSAS be stored?
FerAppease should be kept at controlled room temperature between 10–30℃ (50–86℉). Do not refrigerate or freeze.
Is FerAppease mSAS a generic version of another product?
No. FerAppease is a proprietary product developed by FERA Diagnostics & Biologicals.
Is a FerAppease applicator available?
Yes, the FerAppease Pour-On Gun is a specialized applicator designed to administer FerAppease solutions to swine, allowing for precise, controlled dosing directly onto the animals’ skin.
In what sizes is FerAppease available for swine?
FerAppease mSAS is available in two convenient sizes: a 300 mL bottle and 4 L jugs
Is FerAppease patented or trademarked?
Yes. FerAppease is protected under U.S. Patent No. 12,310,937, with additional patents pending. The FerAppease® trademark is registered under No. 7,084,410 as of June 20, 2023.
Can I request the full study data for FerAppease in swine?
Yes. To request the complete swine study data for FerAppease, please email us at inquiry@feraah.com
Diagnostics
Categories
AccuMast & AccuMast Plus
What is AccuMast?
AccuMast is an on-farm diagnostic kit developed by FERA Diagnostics & Biologicals that allows for the accurate differentiation of more than 11 different mastitis pathogens.
What bacteria can AccuMast and AccuMast Plus detect?
AccuMast can accurately detect the following bacteria:
- E. coli
- Klebsiella
- Enterobacter
- Pseudomonas
- Serratia
- S. uberis
- Streptococcus spp.
- Enterococcus
- Lactococcus
- Staphylococcus spp.
- Staphylococcus aureus
AccuMast Plus can distinguish Streptococcus agalactiae (S. agalactiae) from other Streptococcus species.
How quickly does AccuMast provide results?
AccuMast delivers rapid results. Most bacterial organisms grow within 16 hours, and in many cases the causative organism can be identified in as little as 8–10 hours after incubation.
How accurate is AccuMast?
AccuMast has been scientifically proven to be highly accurate, with overall accuracy greater than 98%. In an independent University of Illinois evaluation (Ferreira et al., 2018) of four on‑farm culture systems, AccuMast was identified as the most accurate system for detecting mastitis‑associated pathogens.
Can AccuMast detect Staphylococcus aureus?
AccuMast is the only on-farm diagnostic test that can detect S. aureus with an accuracy of nearly 100%.
Can AccuMast Plus detect Streptococcus agalactiae?
AccuMast Plus can distinguish Streptococcus agalactiae (S. agalactiae) from other Streptococcus species.
What is the difference between AccuMast and AccuMast Plus?
AccuMast Plus provides the same precision and convenience as AccuMast, with an added advantage: it can distinguish Streptococcus agalactiae (S. agalactiae) from other Streptococcus.
Why is it important to know the cause of mastitis?
Identifying the cause of mastitis is critical for effective treatment and prevention. Research shows that only 3–4 out of 10 mastitis cases benefit from antimicrobial therapy, meaning many mild E. coli or culture‑negative cases do not require antibiotics. By adopting pathogen‑based mastitis management, farmers can save significantly on labor, drug costs, and milk discard (ROI up to 10:1). Knowing the specific pathogen also guides prevention strategies—for example, if Staphylococcus aureus is the primary cause, culling infected animals and improving milking routines can reduce the spread of this contagious disease.
Why is it important to distinguish E. coli from Klebsiella mastitis?
Accurate identification matters because treatment outcomes differ. Research shows intramammary antibiotic therapy does not improve cure rates for E. coli mastitis (97% vs. 98%). In contrast, cows with Klebsiella mastitis respond much better to antibiotics, with cure rates of 74% compared to only 18% in untreated animals (Fuenzalida & Ruegg, 2019). AccuMast is the only on‑farm culture system that can reliably distinguish E. coli from Klebsiella, helping farmers make informed treatment decisions.
What is the color‑coding technology of AccuMast?
AccuMast uses patented color‑coding technology to identify mastitis pathogens. Each culture medium contains chromogens bound to enzymatic substrates. When bacteria grow, their unique enzymes release the chromogens, which crystallize around the colony to create a distinct color pattern. This signature coloration makes it easy to distinguish different mastitis‑causing bacteria.
How much do AccuMast and AccuMast Plus cost?
AccuMast and AccuMast Plus cost $7 per milk sample, providing accurate mastitis diagnostics at a cost‑effective rate for herd screening.
What is the shelf life of AccuMast and AccuMast Plus?
AccuMast and AccuMast Plus are manufactured in an ISO 5 environmentally controlled clean room and packaged using proprietary technology. This process ensures a 12‑month shelf life at room temperature. In contrast, other on‑farm culture systems typically last only 2–3 weeks and often spoil before they can be used.
Is an instruction guide for AccuMast and AccuMast Plus available?
Yes. Official AccuMast and AccuMast instruction guides are available and can be downloaded for easy reference:
Is a safety data sheet for AccuMast available?
Yes. An official AccuMast safety data sheet is available and can be downloaded here.
Is technical support available for AccuMast?
Yes. FERA Diagnostics & Biologicals provides 24/7 technical support through our Clinical Support team which can be reached by phone or text at (979) 213-6470. Our team includes five veterinarians, three of whom also hold Ph.D. degrees. Clients have direct access to expert guidance, including the company’s CEO, Rodrigo Bicalho, DVM, Ph.D., a recognized authority in bovine infectious diseases.
AccuStaph
What is AccuStaph?
AccuStaph is an on-farm diagnostic kit developed by FERA Diagnostics & Biologicals that detects Staphylococcus aureus mastitis infections in dairy cows. It is proven to be 100% accurate, cost‑effective, and allows testing of up to four milk samples per kit. AccuStaph helps farmers and veterinarians identify this contagious pathogen early, supporting better herd health and mastitis control.
How accurate is AccuStaph?
AccuStaph has been scientifically proven to be 100% accurate in detecting Staphylococcus aureus infections in dairy cows.
How many milk samples can one AccuStaph kit test?
Each AccuStaph kit can test up to four different milk samples.
Why is it important to test for Staphylococcus aureus mastitis?
Staphylococcus aureus is the most relevant contagious mastitis pathogen. Testing postpartum cows helps control its spread in dairy herds.
Can AccuStaph distinguish new staph infections from chronic cases?
Yes. AccuStaph can differentiate fresh Staphylococcus aureus infections from chronic cows, helping farmers make better herd management decisions.
How much does AccuStaph cost?
AccuStaph is highly affordable at $1.75 per milk sample, making herd screening cost‑effective.
What is the shelf life of AccuStaph?
AccuStaph's shelf life is 12-months from the date of manufacture.
Is technical support available for AccuStaph?
Yes. FERA Diagnostics & Biologicals provides 24/7 technical support through our Clinical Support team which can be reached by phone or text at (979) 213-6470. Our team includes five veterinarians, three of whom also hold Ph.D. degrees. Clients have direct access to expert guidance, including the company’s CEO, Rodrigo Bicalho, DVM, Ph.D., a recognized authority in bovine infectious diseases.
AccuTreat
What is AccuTreat?
AccuTreat is an on-farm diagnostic kit developed by FERA Diagnostics & Biologicals that detects and differentiates Gram‑positive pathogens causing clinical and sub‑clinical mastitis in dairy cows. It is accurate, practical, and affordable, and each package includes four quadplates, with each quadplate capable of testing up to four milk samples. AccuTreat helps farmers and veterinarians adopt pathogen‑based dry cow therapy, guiding antibiotic use only when necessary and supporting better herd health, mastitis control, and cost‑effective management.
Which Gram‑positive pathogens does AccuTreat detect?
AccuTreat is designed to detect Gram‑positive pathogens including Streptococcus, Lactococcus, and Enterococcus, as well as Staphylococcus aureus, Staphylococcus chromogenes, Staphylococcus haemolyticus, and other coagulase‑negative Staphylococci (CNS).
What is the color‑coding technology of AccuTreat?
AccuTreat uses proprietary chromogenic media technology to differentiate Gram‑positive pathogens. Each quad‑plate contains selective media with chromogens linked to biochemical substrates and organism‑specific markers. When bacteria grow, their enzymes release the chromogens, producing distinct colony colors.
How many milk samples can one AccuTreat kit test?
AccuTreat media uses a four‑section quad‑plate system that enables veterinarians and farmers to accurately diagnose the most important Gram‑positive mastitis pathogens that may require antibiotic therapy. Each quad‑plate can test up to four different milk samples, making it efficient and cost‑effective for herd management.
What is dry cow therapy?
Dry cow therapy is a mastitis control strategy used during the dry period to protect udder health. In the United States, more than 90% of dairy operations practice blanket dry cow therapy, where all cows receive treatment at dry‑off to reduce new intra‑mammary infections. Farms with high milk quality and lower mastitis incidence may adopt selective dry cow therapy, treating only cows that show infection risk. With AccuTreat, farmers can accurately identify Gram‑positive pathogens and apply therapy only to cows or quarters that need it, supporting targeted treatment, reduced antibiotic use, and better herd health outcomes.
How should AccuTreat be stored?
AccuTreat may be shipped and stored briefly at room temperature, but upon receipt it should be kept refrigerated at 2–8ºC and away from direct light. The media is light and temperature sensitive, so protect it from heat, moisture, freezing, and contamination. Once opened, refrigeration is recommended.
How much does AccuTreat cost?
AccuTreat costs $3.50 per milk sample, offering accurate mastitis treatment guidance at an affordable price for herd management.
What is the shelf life of AccuTreat?
AccuTreat's shelf life is 12-months from the date of manufacture.
Is an instruction guide for AccuTreat available?
Yes. Official AccuTreat instruction guides are available and can be downloaded for easy reference:
Is technical support available for AccuTreat?
Yes. FERA Diagnostics & Biologicals provides 24/7 technical support through our Clinical Support team which can be reached by phone or text at (979) 213-6470. Our team includes five veterinarians, three of whom also hold Ph.D. degrees. Clients have direct access to expert guidance, including the company’s CEO, Rodrigo Bicalho, DVM, Ph.D., a recognized authority in bovine infectious diseases.
UTid+
What is UTid+?
UTid+ is an in‑clinic culture system for companion animals developed by FERA Diagnostics & Biologicals that helps veterinarians diagnose common bacterial and fungal infections, including urinary tract infections (UTIs), skin conditions, ear disease, and more. By providing rapid and accurate results, UTid+ enables timely, cost‑effective treatment decisions and improves health outcomes for pets while reducing costs and uncertainty for their owners.
How accurate is UTid+?
UTid+ delivers high diagnostic accuracy across bacterial groups.
- Gram‑negative bacteria: 96.4% accuracy
- Gram‑positive Streptococcus: 91.5% accuracy
- Staphylococcus family: 93.8% accuracy
These results are backed by published studies, confirming UTid+ as a proven, reliable diagnostic solution for diverse pathogens.
Which pathogens does UTid+ detect?
UTid+ identifies a broad range of bacteria and fungi commonly associated with companion animal infections. These include Klebsiella spp., E. coli, Pseudomonas spp., Proteus spp., Streptococcus spp., Enterococcus spp., Enterobacter, Serratia, Citrobacter, coagulase‑negative staphylococci such as S. chromogenes and S. haemolyticus, Staphylococcus aureus, Staphylococcus epidermidis, as well as fungal organisms including Malassezia, Candida, Prototheca, and other fungi.
How fast does UTid+ deliver results?
UTid+ culture kits provide diagnostic results in 16 hours or less, compared to the 48 hours often required by traditional bacterial cultures. This faster turnaround enables veterinarians to make timely treatment decisions and improve outcomes for companion animals.
How much does UTid+ cost?
UTid+ costs $12 per milk sample, delivering highly accurate diagnostics across Gram‑negative, Streptococcus, and Staphylococcus bacteria for effective herd management.
How should UTid+ be stored?
UTid+ may be shipped and stored for brief periods at room temperature. Refrigerate the package for long-term storage.
What is the shelf life of UTid+?
The shelf life of UTid+ is 12-months from the date of manufacture.
Is an instruction guide for UTid+ available?
Yes. Official UTid+ instruction guides are available and can be downloaded for easy reference:
Is technical support available for UTid+?
Yes. FERA Diagnostics & Biologicals provides 24/7 technical support through our Clinical Support team which can be reached by phone or text at (979) 213-6470. Our team includes five veterinarians, three of whom also hold Ph.D. degrees. Clients have direct access to expert guidance, including the company’s CEO, Rodrigo Bicalho, DVM, Ph.D., a recognized authority in bovine infectious diseases.