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Shift Your Cattle from Surviving to Thriving

Did you know that stress shifts your cattle's metabolism into survival mode? Stress may lead to decreasing weight gain and feed conversion and worsening health outcomes. Stress is a major obstacle keeping the cattle industry from becoming a more profitable endeavor. You can overcome stress with FerAppease.

The active ingredient of FerAppease is a synthetic analogue of the Maternal Bovine Appeasing Substance (mBAS). mBAS is a naturally occurring substance that is secreted by the skin of the mammary gland of lactating animals, reducing stress in all cattle treated.

Block the Stress. Face Fewer Costly Challenges!

FerAppease can and should be used every time cattle are exposed to management and physiological stressors, where suppression of threat perception is desirable.

Parturition
Breeding
Weaning
Dehorning
Castration

Branding
Commingling
Arrival
Processing

Reimplantation
Revaccination
Terminal Sorting
Transportation

Threat Perception

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Without FerAppease

The amygdala responds quickly to potential threats in the environment and plays a key role in determining whether environments are perceived as safe or dangerous.

Threat perception leads to activation of the hypothalamic-pituitary-adrenal (HPA) axis leading to increased release of the glucocorticoid hormone cortisol from the adrenal glands and increased release of adrenaline.

Threat perception ultimately leads to:

  • Elevated inflammation
  • Immunosuppression
  • Increased risk for BRD
  • Decreased DMI
  • Weight loss
  • Energy inefficiency
  • Increased morbidity
  • Increased mortality
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With FerAppease

Topically administered Maternal Bovine Appeasing Substance (mBAS) is locally assimilated by the vomeronasal organ located in the nasal cavity.

mBAS mediated stimulation of the vomeronasal gland desensitizes regions of the amygdala and the hypothalamus decreasing the perception of threat.

Reduced threat perception leads to:

  • Reduced flight zones
  • Lower levels of Cortisol
  • Lower Substance-P levels
  • Lower inflammation
  • Lower morbidity
  • Lower mortality

FerAppease in the Field

Cow-Calf Operations | Stockers/Backgrounders | Feedlots

Scientific Data

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Over $90/hd ROI

Research published in Translational Animal Science showed FerAppease significantly increased weight gain by 0.17 lbs daily, added an average of 15.6 lbs to hot carcass weight, improved the marbling score to 508.1, and achieved 94.9% Choice or Prime grades.
Full Study
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Weaned Beef Calves

"Across all the studies that we ran, we typically saw a 15-20% increase in average daily gain post-weaning in calves that received the analogue at the time of weaning."

Dr. Reinaldo Fernandes Cooke, PhD
Department of Animal Science
Texas A&M University

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Feedlot

"If you apply FerAppease before the stress of transport [to the feedlot], your average daily gain jumps from 20% to 30%. "

Dr. Reinaldo Fernandes Cooke, PhD
Department of Animal Science
Texas A&M University